![]() ![]() The organizer is believed to involute inward and migrate animally to. Johnson & Volpes Patterns & Experiments in Developmentalīiology. The dorsal blastopore lip (known as the Spemann organizer) is important for making the body plan in amphibian gastrulation. This experiment attempts to repeat Spemann and Mangold's experiment in Xenopus embryos. They used this information to induce the growth of a second neural tube on an already developing embryo. In 1924 Hans Spemann and Hilde Mangold showed that cells transplanted from this "organizer" region of the blastopore lip of one embryo will induce gastrulation in any kind of tissue. This area in the amphibian embryo has since been termed the organizer for its role in cell fate determination. ![]() However, previous experiments show that cells in one area of the developing embryo are determined before gastrulation. In early stages of development in amphibian embryos, very few cells' fates are rigidly determined. Marie Nickle, Franklin and Marshall College, Class of 2001 ![]() Dorsal Lip Transplant in Amphibian Embryos ![]()
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